名稱 | PDGFRA D842V-V658A/BaF3 kinase細(xì)胞株 |
型號(hào) | CBP73333 |
報(bào)價(jià) | ![]() |
特點(diǎn) | PDGFRA D842V-V658A/BaF3 |
產(chǎn)品搜索
相關(guān)文章
- GLP-1受體激動(dòng)劑細(xì)胞篩選模型
- 自身免疫疾病潛力靶點(diǎn)——IL-5藥篩細(xì)胞模型
- 免疫治療的下一個(gè)靶標(biāo):腫瘤相關(guān)巨噬細(xì)胞?
- 有關(guān)腫瘤細(xì)胞的基因突變研究講解
- 細(xì)胞株培養(yǎng)對(duì)于培養(yǎng)液的要求及相關(guān)常識(shí)說(shuō)明
- 示蹤細(xì)胞在活體成像技術(shù)中的應(yīng)用
- 【論文作者回應(yīng)】小蘇打“餓死”腫瘤?教授為你答疑解惑
- FH標(biāo)準(zhǔn)品上新
- 中國(guó)細(xì)胞資源庫(kù),南京科佰生物
- 官宣!Ba/F3激酶穩(wěn)定細(xì)胞株&科佰激酶篩選平臺(tái)
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73333PDGFRA D842V-V658A/BaF3 kinase細(xì)胞株

- 詳細(xì)內(nèi)容
CBP73333 | |
I. Introduction | |
Cell Line Name: | PDGFRA D842V-V658A/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
PDGFRA D842V lies within the protein kinase domain of the Pdgfra protein (UniProt.org). D842V results in ligand-independent phosphorylation of Pdgfra, activation of downstream signaling, and is transforming in culture (PMID: 22745105, PMID: 23752188, PMID: 29533785, PMID: 30253204) and confers resistance to PDGFRA inhibitors (PMID: 30389923, PMID: 18955458). | |
III. Representative Data | |
1.Sanger of PDGFRA D842V-V658A/BaF3
Figure 1. PDGFRA D842V-V658A/BaF3 V658A Figure 2. PDGFRA D842V-V658A/BaF3 D842V | |
2. Anti-proliferation assay | |
Figure 3. CTG Proliferation Assay of BaF3 PDGFRA D842V/V658A Cells (C1). |